Structural Differences Observed in Arboviruses of the Alphavirus and Flavivirus Genera

Figure 7

Electron micrographs of negatively stained furin sensitive double mutant E1-392/E2-341 containing virus recovered from the supernatant of transfected BHK-21 cells. (A) Low magnification of a typical sample of double mutant E1-392/E2-341. Bar, 1 μm. ((B)–(Q)). Selected particles demonstrating the variations seen in one preparation of E1-392/E2-341. Arrowheads show points of helical disruption and reinitiation. Bars, 100 nm. Kononchik et al. 2009 [53].