Figure 1: Potential link between vitamin D and miR controlling DENV-induced inflammatory response and antiviral activity. (1) DENV replication products and proteins are recognized by several PRRs whose signaling pathways promote the proinflammatory response. (2) Vitamin D activity induces transcription of microRNAs and other target genes that play a critical role in the control of inflammation-related signaling pathways and antiviral activity.