Review Article

Adapted Lethality: What We Can Learn from Guinea Pig-Adapted Ebola Virus Infection Model

Figure 1

Adaptation series of wild-type Mayinga strain EBOV to guinea pigs and mice resulting in the establishment of 8mc, K-5, GLA, and GPA-P7 lethal guinea pig-adapted virus variants and a paradoxical high-titer, avirulent mouse-adapted virus variant D-5.