Research Article
Comparison of the Immunogenicity and Safety of Two Pediatric TBE Vaccines Based on the Far Eastern and European Virus Subtypes
Table 3
Characteristics of local and systemic reactions in children vaccinated with Tick-E-Vac and FSME-IMMUN Junior.
| Vaccination | Reaction | Vaccine (T, I) | Number of subjects (%) | Severity | Onset interval (days) | Duration (days) |
| Conventional schedule | 1 | Local | T | 7/14.3 | 1 | 1 | 1–2 | I | 8/19.0 | 1–2 | 1–2 | 1–3 | Systemic | T | 6/12.2 | 1–2 | 1 | 1–3 | I | 10/23.8 | 1–2 | 1–2 | 1–3 |
| 2 | Local | T | 3/6.1 | 1–2 | 1–3 | 1 | I | 2/4.8 | 1 | 1 | 2 | Systemic | T | 5/10.2 | 1–3 | 1–3 | 3 or more | I | 11/26.2 | 1–2 | 1–2 | 3 or more |
| Rapid schedule | 1 | Local | T | 2/7.4 | 1 | 1 | 1 | I | 5/17.9 | 1 | 1 | 2 | Systemic | T | 6/22.2 | 1–2 | 1–2 | 1–4 | I | 4/14.3 | 1 | 1 | 1–2 |
| 2 | Local | T | — | — | — | — | I | 1/3.6 | 1 | 1 | 3 | Systemic | T | 2/7.4 | 1 | 2 | 2 | I | — | — | — | — |
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T, Tick-E-Vac; I, FSME-IMMUN Junior. Severity scores (see Materials and Methods). |