Research Article

Comparison of the Immunogenicity and Safety of Two Pediatric TBE Vaccines Based on the Far Eastern and European Virus Subtypes

Table 3

Characteristics of local and systemic reactions in children vaccinated with Tick-E-Vac and FSME-IMMUN Junior.

VaccinationReactionVaccine (T, I)Number of subjects (%)SeverityOnset interval (days)Duration (days)

Conventional schedule
1LocalT7/14.3111–2
I8/19.01–21–21–3
SystemicT6/12.21–211–3
I10/23.81–21–21–3

2LocalT3/6.11–21–31
I2/4.8112
SystemicT5/10.21–31–33 or more
I11/26.21–21–23 or more

Rapid schedule
1LocalT2/7.4111
I5/17.9112
SystemicT6/22.21–21–21–4
I4/14.3111–2

2LocalT
I1/3.6113
SystemicT2/7.4122
I

T, Tick-E-Vac; I, FSME-IMMUN Junior. Severity scores (see Materials and Methods).