Research Article

Dysregulation in Plasma ω3 Fatty Acids Concentration and Serum Zinc in Heavy Alcohol-Drinking HCV Patients

Table 2

Liver injury, nutritional status, and serum nutrients in the study cohorts.

Groups/measuresHCV patientsAUDHealthy volunteers (Gr. 5)
HCV-only (Gr. 1)HCV + AUD (Gr. 2)AUD without liver injury (Gr. 3)AUD with liver injury (Gr. 4)

Liver panel
ALT (U/L)102.62 ± 54.85121.68 ± 74.2626.40 ± 8.4484.48 ± 33.5523.92 ± 8.65
AST (U/L)88.85 ± 43.82112.84 ± 64.4125.02 ± 12.99122.65 ± 80.3033.67 ± 21.1
AST : ALT ratio0.89 ± 0.241.03 ± 0.421.01 ± 0.481.44 ± 0.831.39 ± 0.53
Tbili (μmol/L)0.68 ± 0.230.71 ± 0.390.69 ± 0.610.72 ± 0.610.73 ± 0.70
ALB (g/dL)4.02 ± 0.363.83 ± 0.324.10 ± 0.324.10 ± 0.464.05 ± 0.32

Serum zinc and CONUT
Zn (mcg/dL)70.23 ± 11.5363.50 ± 17.4079.20 ± 11.2572.89 ± 26.8072.10 ± 15.73
CONUT score1.17 ± 0.941.78 ± 1.280.85 ± 1.131.23 ± 1.551.10 ± 1.31

ω3 and ω6 polyunsaturated fatty acids participating in inflammation in AUD and HCV + AUD patients. ALT: alanine transaminase; AST: aspartate transaminase; Tbili: Total bilirubin; ALB: albumin; Zn: serum zinc; CONUT: Controlling Nutritional Status.