Advances in Virology / 2020 / Article / Tab 1

Research Article

HBV Core Promoter Inhibition by Tubulin Polymerization Inhibitor (SRI-32007)

Table 1

Activity of SRI-32007 in the HBV virus yield assay in HepG2.2.2.15 cells.

CompoundHBV virus yield assayHBe Ag in culture supernatant
EC50 (nM)CC50 (nM)Selectivity index (CC50/EC50)EC50 (nM)CC50 (nM)Selectivity index (CC50/EC50)

SRI-3200760.14337.2804335.4
Lamivudine/3 TC20>2000>100>2000>2000>1

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.