Advances in Virology / 2020 / Article / Tab 1

Research Article

HBV Core Promoter Inhibition by Tubulin Polymerization Inhibitor (SRI-32007)

Table 1

Activity of SRI-32007 in the HBV virus yield assay in HepG2.2.2.15 cells.

CompoundHBV virus yield assayHBe Ag in culture supernatant
EC50 (nM)CC50 (nM)Selectivity index (CC50/EC50)EC50 (nM)CC50 (nM)Selectivity index (CC50/EC50)

Lamivudine/3 TC20>2000>100>2000>2000>1

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