Di-n-butyltin(IV) Complexes Derived from Heterocyclic β-diketones and N-Phthaloyl Amino Acids: Preparation, Biological Evaluation, Structural Elucidation Based upon Spectral [IR, NMR (¹H, ¹³C, ¹⁹F and ¹¹⁹Sn)] Studies

Abstract

Stable, six coordinated Bu₂SnLA type complexes have been prepared [where LH = RCOC:C(OH)N(C6H5)N:︹CCH3; R = -4-F-C₆H₄-(L¹H), R = -4-Cl-C₆H₄-(L²H), R= -4-Br-C₆H₄-(L³H), R= -CF₃(L⁴H) and AH=C(O)C6H4C(O)︹NCHR′COOH; R'= -H(A¹H), -CH₃(A²H), -CH(CH₃)₂(A³H)] by the interaction of 1:1:1 molar ratios of di-n-butyltin(IV) dichloride with corresponding organic moieties in refluxing benzene using two moles of Et₃N as a base. In these complexes LH and AH behave as bidentate and coordination is taking place through oxygen, this is inferred from IR and ¹³C NMR studies. These complexes possess tin atoms in skew trapezoidal bipyramidal geometry with the C-Sn-C angles ranging from 149.88^° to 156.84^°. Some of these complexes with their corresponding organic moieties (LH, AH) were tested for their antimicrobial activities.