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Bioinorganic Chemistry and Applications
Volume 2006, Article ID 17316, 10 pages

Fertility Regulation in Male Rats by Implemented Tetraazamacrocyclic Compounds of Iron(II): Synthetic, Spectroscopic, and Applied Aspects with Toxicological Screening

Department of Chemistry, University of Rajasthan, Jaipur, Rajasthan 302 004, India

Received 12 August 2004; Revised 18 October 2004; Accepted 25 November 2004

Copyright © 2006 Ashu Chaudhary and Ran Vir Singh. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Antifertility and histopathological investigations were carried out on reproductive organs of male albino rats induced by tetraazamacrocyclic complexes of iron(II). The complexes were synthesized by the template condensation of 1,2-diaminoethane, 1,3-diaminopropane with succinic acid and phthalic acid in 2:2 molar ratios which are abbreviated as [Fe(TAMLn)OAc] (n=1 or 2 and TAMLn represents tetraazamacrocyclic ligand). The complexes have been characterized by elemental analysis, conductivity measurements, IR, and electronic spectra.