Fertility Regulation in Male Rats by Implemented Tetraazamacrocyclic Compounds of Iron(II): Synthetic, Spectroscopic, and Applied Aspects with Toxicological Screening

Chaudhary, Ashu; Singh, Ran Vir

doi:https://doi.org/10.1155/BCA/2006/17316

Bioinorganic Chemistry and Applications

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Volume 2006 | Article ID 017316 | https://doi.org/10.1155/BCA/2006/17316

Fertility Regulation in Male Rats by Implemented Tetraazamacrocyclic Compounds of Iron(II): Synthetic, Spectroscopic, and Applied Aspects with Toxicological Screening

Ashu Chaudhary¹and Ran Vir Singh¹

Received12 Aug 2004

Revised18 Oct 2004

Accepted25 Nov 2004

Published21 May 2006

Abstract

Antifertility and histopathological investigations were carried out on reproductive organs of male albino rats induced by tetraazamacrocyclic complexes of iron(II). The complexes were synthesized by the template condensation of 1,2-diaminoethane, 1,3-diaminopropane with succinic acid and phthalic acid in 2:2 molar ratios which are abbreviated as [Fe(TAMLn)OAc] (n=1 or 2 and TAMLn represents tetraazamacrocyclic ligand). The complexes have been characterized by elemental analysis, conductivity measurements, IR, and electronic spectra.

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Copyright © 2006 Ashu Chaudhary and Ran Vir Singh. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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