In Vitro Evaluation of a Stable Monomeric Gold(II) Complex with Hematoporphyrin IX: Cytotoxicity against Tumor and Kidney Cells, Cellular Accumulation, and Induction of Apoptosis
Figure 4
Internucleosomal DNA
fragmentation in SKW-3, K-562, HD-MY-Z, and MGH-U1 cells after 24-hour exposure to
equipotent concentrations of [Au(II).] (white columns) or cisplatin (gray
columns). The level of DNA fragmentation expressed as the corresponding enrichment factor
( in untreated control) was determined using “Cell Death Detection”
ELISA (Roche Diagnostics).
