Research Article
Synthesis, Characterization, and Biological Studies of Organotin(IV) Derivatives with o- or p-hydroxybenzoic Acids
Table 4
values
for LOX inhibition activity and
cell cytotoxic activity of
organotin(IV) complexes
1–
6.
| Compound | for LOX inhibition | cell
activity | Ref |
| Sn (1) | 76 m | 2000 nm | | Sn
(2) | 48 m | 150 nm | | Sn (3) | 82 m | 150 nm | | Sn (4) | 19 m | 5-10 nm | | Sn (5) | 24 m | 30-40 nm | | Sn (6) | 11 m | 25-35 nm | | Sn | 25 m | 125 nM | [14] | Sn(MNA)Sn(acetone)] | 14 m | 5 nm | [14] | Sn(MBZT)] | 19 m | 1500–3000 nm | [15] | Sn(MBZO)] | 16 m | 1300–3000 nm | [15] | Sn(CMBZT)] | 21 m | 500–800 nM | [15] | Sn | 10 m | 300–500 nm | [15] | Sn | 13 m | 600–800 nm | [15] | Sn | 14 m | 5000–7500 nm | [15] | Sn | 61 m | 20000–60000 nm | [16] | Sn | 26 m | 700 nm | [16] | Sn | 21 m | 1000–2000 nm | [16] | Sn(PMT)] | 17 m | 100 nm | [16] |
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: This work; HTBA: 2-thiobarbituric
acid; MNA:
2-mercapto-nicotinic acid;
MBZT: 2-mercapto-benzothiazole; MBZO: 2-mercapto-benzoxazole; CMBZT:
5-chloro-2-mercapto-benzothiazole; HPMT: 2-mercapto-pyrimidine.
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