DNA Oxidative Cleavage Induced by the Novel Peptide Derivatives of 3-(quinoxalin-6-yl)alanine in Combination with Cu(II) or Fe(II) Ions

Figure 3

(a) Pattern of the plasmid DNA damage by DPQa-Gly complexes with selected transition metal ions in the presence of H₂O₂ (lanes 2–7) and ascorbate (lanes 8–13). Untreated DNA, lane 1; (b) Densitogram of the gel presented in Figure 3(a); grey bars represent relative amounts of the nicked plasmid (form II), black bars represent relative amounts of linear plasmid (form III).

(a)

(b)