Investigation on the Interactions of NiCR and NiCR-2H with DNA
Figure 6
Autoradiogram demonstrating cleavage of 1 by NiCR (30 M) and NiCR-2H (30 M). Lane 1: intact DNA; Lane 2: Maxam-Gilbert G-sequencing of 1; Lane 3–8: DNA incubated with NiCR in the presence of 0.1, 0.2, 0.4, 0.75, 1 mM KHSO5, respectively; Lane 9–14: DNA incubated with NiCR-2H in the presence of 0.1, 0.2, 0.4, 0.75, 1 mM , respectively.