Synthetic Peptides as Structural Maquettes of Angiotensin-I Converting Enzyme Catalytic Sites

Figure 3

(a) Short-, medium-, and long-range connectivities. (b) Number of NOE constraints per residue (white, gray, dark gray, and black vertical bars represent, resp., intraresidue, sequential, medium-range, and long-range connectivities). (c) Schematic representation of the sequential and medium range NOEs involving HN, Hα, and H_β protons for Zn²⁺-ACE_C(37) (corresponds to His⁹⁵⁸-Ala⁹⁹⁴ of the human somatic form).

(a)

(b)

(c)