Research Article

Diorganotin Complexes of a Thiosemicarbazone, Synthesis: Properties, X-Ray Crystal Structure, and Antiproliferative Activity of Diorganotin Complexes

Table 4

The antiproliferative activity in vitro of 1–4, expressed as as IC50 ± SD ( M) against MCF-7, T-24, A-549, and L-929 cancer cell lines.

L929A549T24MCF7

H2L (1) 0.81± 0.02 0.153 0.01
SnM (L)] (2) 9.04 ± 0.05 2920.79 0.03
SnB (L)] (3) 0.77 ± 0.03
SnP (L)] (4) 0.83 ± 0.020.73 0.02

M SnO 60717.9 ± 0.86 607
B SnO 40210.4 ± 0.41 402
P SnO 3463.5 0.02

cisplatin