Bioinorganic Chemistry and Applications

Research Article

Studies of the Antiproliferative Activity of Ruthenium (II) Cyclopentadienyl-Derived Complexes with Nitrogen Coordinated Ligands

Table 2

IC50 values of ruthenium compounds, and cisplatin against HL-60 cells.
ComplexIC50 ( M)72 hoursIC50 ( M) 24 hours
10.69 ± 0.160.95 ± 0.15
20.53 + 0.050.57 + 0.09
30.94 + 0.0851.46 + 0.25
42.26 + 0.535.89 + 0.67
CDDP2.15 + 0.115.61 + 1.15