Selectivity of Inhibition of N-Succinyl-l,l-Diaminopimelic Acid Desuccinylase in Bacteria: The product of dapE-gene Is Not the Target of l-Captopril Antimicrobial Activity

Table 3

Inhibiton of Salmonella enterica growth by L-captopril.

DapE-knockout strains	TN5935; (Plasmid with dapE gene)		TN5959; (Plasmid without dapE gene)
Supplemented with mDAP	Yes	No	Yes	No
	Radius of zone of inhibition by L-captopril
25 mg/mL	0.1 cm	0.1 cm	0.0 cm	No growth
50 mg/mL	0.5 cm	0.5 cm	0.1 cm	No growth
20 mg	1.7 cm	1.7 cm	1.7 cm	No growth