Synthesis Characterization and Biological Activity Study of New Schiff and Mannich Bases and Some Metal Complexes Derived from Isatin and Dithiooxamide

Table 1

Physical properties and analytical data of the prepared Schiff and Mannich base complexes.

Molecular formula; (Color)	m.p. (decomposition); temp. °C	Yield %	% element analysis found (calculated)
			C	H	N	M	Cl
[Mn(LIH)(H2O)Cl2] 2.5H2O (Brown) (C1)	215	42.24	33.91; (33.46)	4.22; (4.27)	11.18; (10.40)	10.66; (10.20)	13.11; (13.19)
[Co(LIH)(NO3)2]H2O (Brown) (C2)	174	61.11	33.11; (32.77)	3.02; (3.27)	16.09; (15.29)	10.50; (10.73)	—
[Ni(LIH)2]2NO3·H2O (Bright blue) (C3)	>300	50.8	40.90; (40.13)	3.62; (3.78)	16.06; (15.60)	5.78; (6.54)	—
[Cu2(LIH)2Cl(H2O)4]Cl3  (Reddish brown) (C4)	>300	77.11	40.25; (39.85)	4.32; (4.43)	6.81; (6.20)	13.73; (14.07)	7.26; (7.86)
[PdLI]Cl·1.5H2O (Dark brown) (C5)	250	59.21	34.45; (34.82)	3.01; (3.48)	11.32; (10.80)	—	7.01; (6.86)
[Ir(LIH)2Cl2]Cl·H2O (Pale yellow) (C6)	230	32.31	34.73; (35.51)	3.32; (3.55)	11.82; (11.05)	19.56; (19.12)	9.98; (10.50)
[Pt(LI)Cl3]0.5H2O (Yellow brown) (C7)	>300	34.01	27.78; (27.31)	2.49; (2.58)	8.82; (8.49)	28.89; (29.60)	16.82; (16.16)
[Co2(LIIH)2(NO3)4]·2H2O (Dark green) (C8)	235	42.15	44.62; (43.74)	3.71; (3.17)	13.64; (13.31)	8.89; (9.34)	—
[Ni(LIIH)(OAc)2] (Blue) (C9)	243	50.32	52.84; (53.40)	3.54; (3.95)	9.43; (9.23)	9.72; (9.23)	—
[PdLIICl]21.5H2O (Dark brown) (C10)	>280	23.30	46.51; (46.86)	3.81; (3.23)	10.11; (9.51)	—	6.40; (6.03)
[Pt(LII)Cl2·H2O]Cl·H2O (Brown) (C11)	250	33.23	36.21; (35.95)	2.13; (2.87)	8.23; (7.29)	24.77; (25.40)	13.09; (13.87)
[CdLII (OAc)(H2O)2]2 (Yellow) (C12)	260	20.57	46.65; (47.06)	3.62; (3.29)	9.50; (8.77)	16.95; (17.63)	—