Sensitive Marker of the Cisplatin-DNA Interaction: X-Ray Photoelectron Spectroscopy of CL
Figure 1
(a) High-resolution XPS spectra of Cl 2p for cisplatin in solid phase and in H2O. (b) Cl 2p spectra for cisplatin-oligo complex at ratio of 8 : 1 with the increasing incubation time. The peaks are deconvoluted to covalent and ionic Cl (two coupled dashed lines), respectively. The straight line is used to point out the relative position of covalent Cl. (c) The binding energy of ionic Cl 2p3/2 corresponding to (b) as a function of incubation time.
