Spectroscopic Characterization and Biological Activity of Mixed Ligand Complexes of Ni(II) with 1,10-Phenanthroline and Heterocyclic Schiff Bases

Table 5

IC₅₀ range of Ni(II) complexes for HeLa cells.

Complex	IC50 (μg/mL)
[Ni (1,10-phen) (MIIMP) (H2O)2]Cl	65.48±0.18
[Ni (1,10-phen) (CMIIMP) (H2O)2]Cl	68.32±0.21
[Ni (1,10-phen) (EMIIMP) (H2O)2]Cl	35.48±0.12
[Ni (1,10-phen) (MIIMNP) (H2O)2]Cl	50.84±0.43
[Ni (1,10-phen) (MEMIIMP) (H2O)2]Cl	47.31±0.85
[Ni (1,10-phen) (MMIIMP) (H2O)2]Cl	71.25±0.42
[Ni (1,10-phen) (BMIIMP) (H2O)2]Cl	82.30±0.24
[Ni (1,10-phen) (MIIBD) (H2O)2]Cl	52.51±0.72