Coordination Dynamics and Coordination Mechanism of a New Type of Anticoagulant Diethyl Citrate with Ca²⁺ Ions

Table 1

Reaction rate constant and reaction order of Et₂Cit and Na₃Cit with Ca²⁺ ions.

pH	6.0	7.4	8.0
Et2Cit-CaCl2 system
reaction order (𝑛)	2.03	2.46	2.73
stability constants (𝐾𝑠)	10^0.93	10^2.06	10^3.06
rate constant (𝑘)/L·mol^−1·s^−1	9	120	4571
reverse reaction rate constant (𝑘re)/L·mol^−1·s^−1	0.04	0.52	19.80
Na3Cit-CaCl2 system
reaction order (𝑛)	2.16	2.44	3.0
𝐾𝑠	10^1.98	10^2.46	10^4.83
𝑘/L·mol^−1·s^−1	60	289	13489
𝑘re/L·mol^−1·s^−1	0.03	0.15	6.79