Synthesis, Characterization, and Bioactivity of Schiff Bases and Their Cd^𝟐+, Zn^𝟐+, Cu^𝟐+, and Ni^𝟐+ Complexes Derived from Chloroacetophenone Isomers with S-Benzyldithiocarbazate and the X-Ray Crystal Structure of S-Benzyl-β-N-(4-chlorophenyl)methylenedithiocarbazate

Table 8

Ratio of mean inhibition zone diameter of synthesized compounds to that of reference compounds.

	S. aureus	B. cereus	K. rhizophila	E. coli	P. aeruginosa	C. freundii	Aspergillus  niger
NS2
Streptomycin	1.25	1.38	1.56	1.08	1.03	Not available
Neomycin	0.97	1.17	1.02	0.94	0.63	1.04
Chloramphenicol	0.68	1.00	0.73	Control has no effect	0.92	0.99
SBDTC	0.92	0.95	1.43	0.99	0.93	0.92	0.00
Amphotericin B							0.00
Zn(NS2)2
Streptomycin	1.15	1.16	1.50	0.60	1.00	Not available
Neomycin	0.89	0.98	0.99	0.52	0.62	0.90
Chloramphenicol	0.63	0.84	0.71	Control has no effect	0.91	0.86
SBDTC	0.85	0.80	1.38	0.55	0.91	0.80	1.25
Amphotericin B							1.21
Cd(NS2)2
Streptomycin	0.63	0.52	2.11	0.51	1.13	Not available
Neomycin	0.49	0.44	1.39	0.45	0.70	0.44
Chloramphenicol	0.34	0.38	1.00	Control has no effect	1.02	0.42
SBDTC	0.47	0.36	1.93	0.47	1.02	0.39	1.61
Amphotericin B							1.56
Ni(NS2)2
Streptomycin	0.53	0.54	1.11	0.00	0.66	Not available
Neomycin	0.41	0.46	0.73	0.00	0.41	0.00
Chloramphenicol	0.29	0.39	0.52	Control has no effect	0.59	0.00
SBDTC	0.39	0.37	1.02	0.00	0.60	0.00	0.92
Amphotericin B							0.90
Cu(NS2)2
Streptomycin	0.50	0.00	0.00	0.00	0.55	Not available
Neomycin	0.39	0.00	0.00	0.00	0.34	0.00
Chloramphenicol	0.27	0.00	0.00	Control has no effect	0.50	0.00
SBDTC	0.37	0.00	0.00	0.00	0.50	0.00	0.00
Amphotericin B							0.00
NS4
Streptomycin	0.00	0.42	0.00	0.00	0.00	Not available
Neomycin	0.00	0.35	0.00	0.00	0.00	0.61
Chloramphenicol	0.00	0.30	0.00	Control has no effect	0.00	0.58
SBDTC	0.00	0.29	0.00	0.00	0.00	0.54	0.00
Amphotericin B							0.00
Zn(NS4)2
Streptomycin	0.65	0.52	0.61	0.00	0.00	Not available
Neomycin	0.51	0.44	0.40	0.00	0.00	0.51
Chloramphenicol	0.36	0.38	0.29	Control has no effect	0.00	0.49
SBDTC	0.48	0.36	0.56	0.00	0.00	0.46	0.00
Amphotericin B							0.00
Cd(NS4)2
Streptomycin	0.55	0.42	2.46	0.00	0.00	Not available
Neomycin	0.43	0.36	1.62	0.00	0.00	0.36
Chloramphenicol	0.30	0.30	1.16	Control has no effect	0.00	0.34
SBDTC	0.41	0.29	2.25	0.00	0.00	0.32	0.00
Amphotericin B							0.00
Ni(NS4)2
Streptomycin	0.77	0.65	0.75	0.00	0.00	Not available
Neomycin	0.60	0.55	0.49	0.00	0.00	0.69
Chloramphenicol	0.42	0.47	0.35	Control has no effect	0.00	0.66
SBDTC	0.57	0.45	0.68	0.00	0.00	0.61	0.00
Amphotericin B							0.00
Cu(NS4)2
Streptomycin	0.73	0.42	0.67	0.00	0.00	Not available
Neomycin	0.57	0.36	0.44	0.00	0.00	0.53
Chloramphenicol	0.40	0.31	0.32	Control has no effect	0.00	0.50
SBDTC	0.54	0.29	0.62	0.00	0.00	0.47	0.00
Amphotericin B							0.00