Synthesis, Characterization, and Interaction with Biomolecules of Platinum(II) Complexes with Shikimic Acid-Based Ligands

<table class="table-group" id="tab5"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left"> </td><td align="center">Dip G1 (%)</td><td align="center">Dip G2 (%)</td><td align="center">Dip S (%)</td></tr><tr><td align="left" colspan="4"><hr/></td></tr><tr><td align="left">Pt(Lb)Cl2</td><td align="center">49.26</td><td align="center">27.09</td><td align="center">23.64</td></tr><tr><td align="left">Pt(Lc)Cl2</td><td align="center">50.57</td><td align="center">21.21</td><td align="center">28.22</td></tr><tr><td align="left">Untreated</td><td align="center">49.92</td><td align="center">14.74</td><td align="center">35.34</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Induction of cell-cycle arrest in BEL7404 cells after treatment with PtLbCl2, PtLcCl2.

Bioinorganic Chemistry and Applications

tab5

Table 5

Table 5: Synthesis, Characterization, and Interaction with Biomolecules of Platinum(II) Complexes with Shikimic Acid-Based Ligands 