Table of Contents Author Guidelines Submit a Manuscript
Bioinorganic Chemistry and Applications
Volume 2014, Article ID 568741, 13 pages
http://dx.doi.org/10.1155/2014/568741
Research Article

Synthesis, Structural Characterization, and Biological Activity Studies of Ni(II) and Zn(II) Complexes

Department of Chemistry, National Institute of Technology, Warangal 506 004, India

Received 28 October 2013; Accepted 26 March 2014; Published 28 April 2014

Academic Editor: Imre Sovago

Copyright © 2014 Palakuri Kavitha and K. Laxma Reddy. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. K. Singh, A. Srivastava, A. Sodhi, and P. Ranjan, “In vitro and in vivo antitumour studies of a new thiosemicarbazide derivative and its complexes with 3d-metal ions,” Transition Metal Chemistry, vol. 25, no. 2, pp. 133–140, 2000. View at Google Scholar · View at Scopus
  2. N. Raman, K. Pothiraj, and T. Baskaran, “DNA interaction, antimicrobial, electrochemical and spectroscopic studies of metal(II) complexes with tridentate heterocyclic Schiff base derived from 2′-methylacetoacetanilide,” Journal of Molecular Structure, vol. 1000, no. 1–3, pp. 135–144, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. C. Yuan, L. Lu, Y. Wu et al., “Synthesis, characterization, and protein tyrosine phosphatases inhibition activities of oxovanadium(IV) complexes with Schiff base and polypyridyl derivatives,” Journal of Inorganic Biochemistry, vol. 104, no. 9, pp. 978–986, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. Y. Li, Z.-Y. Yang, and J.-C. Wu, “Synthesis, crystal structures, biological activities and fluorescence studies of transition metal complexes with 3-carbaldehyde chromone thiosemicarbazone,” European Journal of Medicinal Chemistry, vol. 45, no. 12, pp. 5692–5701, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. Y. S. Shim, K. C. Kim, D. Y. Chi, K.-H. Lee, and H. Cho, “Formylchromone derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors,” Bioorganic and Medicinal Chemistry Letters, vol. 13, no. 15, pp. 2561–2563, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. K. M. Khan, N. Ambreen, U. R. Mughal, S. Jalil, S. Perveen, and M. I. Choudhary, “3-formylchromones: potential antiinflammatory agents,” European Journal of Medicinal Chemistry, vol. 45, no. 9, pp. 4058–4064, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. G. Mhaske, P. Nilkanth, A. Auti, S. Davange, and S. Shelke, “Aqua medicated, microwave assisted, synthesis of Schiff bases and their biological evaluation,” International Journal of Innovative Research in Science, Engineering and Technology, vol. 3, pp. 8156–8162, 2014. View at Google Scholar
  8. M. T. Hussain, N. H. Rama, and K. M. Khan, “A novel unusual isocoumarin derivative, 3H-Furo[3, 4-c] isochromene-1, 5-dione,” Letters in Organic Chemistry, vol. 7, no. 7, pp. 557–560, 2010. View at Publisher · View at Google Scholar
  9. A. A. Osowole, “Synthesis, characterization, in-vitro antibacterial and anticancer studies on some metal(II) complexes of (methylsulfanyl)chromenol Schiff base,” Elixir Applied Chemistry, vol. 39, pp. 4827–4831, 2011. View at Google Scholar
  10. K. M. Khan, A. Ahmad, N. Ambreen et al., “Schiff bases of 3-formylchromones as antibacterial, antifungal, and phytotoxic agents,” Letters in Drug Design and Discovery, vol. 6, no. 5, pp. 363–373, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Bhatnagar, S. Sahi, P. Kackar et al., “Synthesis and docking studies on styryl chromones exhibiting cytotoxicity in human breast cancer cell line,” Bioorganic and Medicinal Chemistry Letters, vol. 20, no. 16, pp. 4945–4950, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. A. Gomes, O. Neuwirth, M. Freitas et al., “Synthesis and antioxidant properties of new chromone derivatives,” Bioorganic & Medicinal Chemistry, vol. 17, no. 20, pp. 7218–7226, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. L. Z. Piao, H. R. Park, Y. K. Park, S. K. Lee, J. H. Park, and M. K. Park, “Mushroom tyrosinase inhibition activity of some chromones,” Chemical and Pharmaceutical Bulletin, vol. 50, no. 3, pp. 309–311, 2002. View at Publisher · View at Google Scholar · View at Scopus
  14. S. A. Patil, S. N. Unki, A. D. Kulkarni, V. H. Naik, and P. S. Badami, “Synthesis, characterization, in vitro antimicrobial and DNA cleavage studies of Co(II), Ni(II) and Cu(II) complexes with ONOO donor coumarin Schiff bases,” Journal of Molecular Structure, vol. 985, no. 2-3, pp. 330–338, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. F. Arjmand, F. Sayeed, and M. Muddassir, “Synthesis of new chiral heterocyclic Schiff base modulated Cu(II)/Zn(II) complexes: their comparative binding studies with CT-DNA, mononucleotides and cleavage activity,” Journal of Photochemistry and Photobiology B: Biology, vol. 103, no. 2, pp. 166–179, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. C. N. Sudhamani, H. S. B. Naik, T. R. R. Naik, and M. C. Prabhakara, “Synthesis, DNA binding and cleavage studies of Ni(II) complexes with fused aromatic N-containing ligands,” Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, vol. 72, no. 3, pp. 643–647, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. D.-D. Qin, Z.-Y. Yang, and B.-D. Wang, “Spectra and DNA-binding affinities of copper(II), nickel(II) complexes with a novel glycine Schiff base derived from chromone,” Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, vol. 68, no. 3, pp. 912–917, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. B.-D. Wang, Z.-Y. Yang, M.-H. Lü, J. Hai, Q. Wang, and Z.-N. Chen, “Synthesis, characterization, cytotoxic activity and DNA binding Ni(II) complex with the 6-hydroxy chromone-3-carbaldehyde thiosemicarbazone,” Journal of Organometallic Chemistry, vol. 694, no. 25, pp. 4069–4075, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. Li, Z. Y. Yang, Z. C. Liao, Z. C. Han, and Z. C. Liu, “Synthesis, crystal structure, DNA binding properties and antioxidant activities of transition metal complexes with 3-carbaldehyde-chromone semicarbazone,” Inorganic Chemistry Communications, vol. 13, no. 10, pp. 1213–1216, 2010. View at Publisher · View at Google Scholar
  20. B.-D. Wang, Z.-Y. Yang, and T.-R. Li, “Synthesis, characterization, and DNA-binding properties of the Ln(III) complexes with 6-hydroxy chromone-3-carbaldehyde-(2′-hydroxy) benzoyl hydrazone,” Bioorganic and Medicinal Chemistry, vol. 14, no. 17, pp. 6012–6021, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. P. Kavitha, M. Saritha, and K. L. Reddy, “Synthesis, structural characterization, fluorescence, antimicrobial, antioxidant and DNA cleavage studies of Cu(II) complexes of formyl chromone Schiff bases,” Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, vol. 102, pp. 159–168, 2013. View at Publisher · View at Google Scholar
  22. P. Kavitha, M. R. Chary, B. V. A. A. Singavarapu, and K. L. Reddy, “Synthesis, characterization, biological activity and DNA cleavage studies of tridentate Schiff bases and their Co(II) complexes,” Journal of Saudi Chemical Society, 2013. View at Publisher · View at Google Scholar
  23. P. Kavitha and K. L. Reddy, “Pd(II) complexes bearing chromone based Schiff bases: synthesis, characterisation and biological activity studies,” Arabian Journal of Chemistry, 2012. View at Publisher · View at Google Scholar
  24. A. Nohara, T. Umetani, and Y. Sanno, “A facile synthesis of chromone-3-carboxaldehyde, chromone-3-carboxylic acid and 3-hydroxymethylchromone,” Tetrahedron Letters, vol. 14, no. 22, pp. 1995–1998, 1973. View at Google Scholar · View at Scopus
  25. I. Sigg, G. Haas, and T. Winkler, “The reaction of 3-formylchromone with ortho-substituted anilines. Preparation of a Tetraaza [14] annulene,” Helevetica Chimica Acta, vol. 65, no. 1, pp. 275–279, 1982. View at Publisher · View at Google Scholar
  26. K. M. Khan, N. Ambreen, S. Hussain, S. Perveen, and M. I. Choudhary, “Schiff bases of 3-formylchromone as thymidine phosphorylase inhibitors,” Bioorganic and Medicinal Chemistry, vol. 17, no. 8, pp. 2983–2988, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. J. E. Stemper and J. M. Matsen, “Device for turbidity standardizing of cultures for antibiotic sensitivity testing,” Applied Microbiology, vol. 19, no. 6, pp. 1015–1016, 1970. View at Google Scholar · View at Scopus
  28. K. Shanker, R. Rohini, V. Ravinder, P. M. Reddy, and Y.-P. Ho, “Ru(II) complexes of N4 and N2O2 macrocyclic Schiff base ligands: their antibacterial and antifungal studies,” Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, vol. 73, no. 1, pp. 205–211, 2009. View at Publisher · View at Google Scholar · View at Scopus
  29. P. C. Trivedi, Nematode Diseases in Plants, CBS, New Delhi, India, 1st edition, 1998.
  30. J. Cayrol, C. Djian, and L. Pijarowski, “Study of the nematicidal properties of the culture filtrate of the nematophagous fungus Paecilomyces lilacinus,” Revue de Nematologie, vol. 12, pp. 331–336, 1989. View at Google Scholar
  31. A. Braca, N. de Tommasi, L. di Bari, C. Pizza, M. Politi, and I. Morelli, “Antioxidant principles from Bauhinia tarapotensis,” Journal of Natural Products, vol. 64, no. 7, pp. 892–895, 2001. View at Publisher · View at Google Scholar · View at Scopus
  32. S. Sathiyaraj, R. J. Butcher, and Ch. Jayabalakrishnan, “Synthesis, characterization, DNA interaction and in vitro cytotoxicity activities of ruthenium(II) Schiff base complexes,” Journal of Molecular Structure, vol. 1030, pp. 95–103, 2012. View at Publisher · View at Google Scholar
  33. W. J. Geary, “The use of conductivity measurements in organic solvents for the characterisation of coordination compounds,” Coordination Chemistry Reviews, vol. 7, no. 1, pp. 81–122, 1971. View at Google Scholar · View at Scopus
  34. A. I. Vogel, A Text Book of Quantitative Inorganic Analysis, Longman, 3rd edition, 1961.
  35. O. A. El-Gammal, G. A. El-Reash, and S. F. Ahmed, “Structural, spectral, thermal and biological studies on 2-oxo-N′-((4-oxo-4H-chromen-3-yl)methylene)-2-(phenylamino)acetohydrazide (H2L) and its metal complexes,” Journal of Molecular Structure, vol. 1007, pp. 1–10, 2012. View at Publisher · View at Google Scholar · View at Scopus
  36. C. Anitha, C. D. Sheela, P. Tharmaraj, and S. J. Raja, “Synthesis and characterization of VO(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes of chromone based azo-linked Schiff base ligand,” Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, vol. 98, pp. 35–42, 2012. View at Publisher · View at Google Scholar
  37. M. Padmaja, J. Pragathi, and C. G. Kumari, “Synthesis, spectral characterization, molecular modeling and biological activity of first row transition metal complexes with Schiff base ligand derived from chromone-3-carbaldehyde and o-amino benzoic acid,” Journal of Chemical and Pharmaceutical Research, vol. 3, no. 4, pp. 602–613, 2011. View at Google Scholar · View at Scopus
  38. B. Kannamba, K. L. Reddy, and B. V. AppaRao, “Removal of Cu(II) from aqueous solutions using chemically modified chitosan,” Journal of Hazardous Materials, vol. 175, no. 1–3, pp. 939–948, 2010. View at Publisher · View at Google Scholar · View at Scopus
  39. S. Chandra and L. K. Gupta, “Spectroscopic and biological studies on newly synthesized nickel(II) complexes of semicarbazones and thiosemicarbazones,” Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, vol. 62, no. 4-5, pp. 1089–1094, 2005. View at Publisher · View at Google Scholar · View at Scopus
  40. P. K. Singh and D. N. Kumar, “Spectral studies on cobalt(II), nickel(II) and copper(II) complexes of naphthaldehyde substituted aroylhydrazones,” Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, vol. 64, no. 4, pp. 853–858, 2006. View at Publisher · View at Google Scholar · View at Scopus
  41. B. E. Warren, X-Ray Diffraction, Dover, New York, NY, USA, 2nd edition, 1990.
  42. X. Huang, Y. Xia, H. Zhang et al., “Synthesis, crystal structure, and fluorescence studies of (1-naphthyl)(pyridyl)urea metal complexes,” Inorganic Chemistry Communications, vol. 11, no. 4, pp. 450–453, 2008. View at Publisher · View at Google Scholar · View at Scopus
  43. A. K. Sharma and S. Chandra, “Complexation of nitrogen and sulphur donor Schiff's base ligand to Cr(III) and Ni(II) metal ions: synthesis, spectroscopic and antipathogenic studies,” Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, vol. 78, no. 1, pp. 337–342, 2011. View at Publisher · View at Google Scholar · View at Scopus
  44. T. A. Yousef, G. M. Abu El-Reash, O. A. El-Gammal, and R. A. Bedier, “Co(II), Cu(II), Cd(II), Fe(III) and U(VI) complexes containing a NSNO donor ligand: synthesis, characterization, optical band gap, in vitro antimicrobial and DNA cleavage studies,” Journal of Molecular Structure, vol. 1029, pp. 149–160, 2012. View at Publisher · View at Google Scholar
  45. H.-L. Seng, H.-K. A. Ong, R. N. Z. R. A. Rahman et al., “Factors affecting nucleolytic efficiency of some ternary metal complexes with DNA binding and recognition domains. Crystal and molecular structure of Zn(phen)(edda),” Journal of Inorganic Biochemistry, vol. 102, no. 11, pp. 1997–2011, 2008. View at Publisher · View at Google Scholar · View at Scopus
  46. S. K. Bharti, S. K. Patel, G. Nath, R. Tilak, and S. K. Singh, “Synthesis, characterization, DNA cleavage and in vitro antimicrobial activities of copper(II) complexes of Schiff bases containing a 2,4-disubstituted thiazole,” Transition Metal Chemistry, vol. 35, no. 8, pp. 917–925, 2010. View at Publisher · View at Google Scholar · View at Scopus
  47. D. S. Sigman, A. Mazumder, and D. M. Perrin, “Chemical nucleases,” Chemical Reviews, vol. 93, no. 6, pp. 2295–2316, 1993. View at Google Scholar · View at Scopus
  48. T. Kobayashi, M. Kunita, S. Nishino et al., “Release of free nucleobases from oligomers by copper(II)-peroxide adduct,” Polyhedron, vol. 19, no. 26-27, pp. 2639–2648, 2000. View at Google Scholar · View at Scopus
  49. T. A. Yousef, G. M. Abu El-Reash, O. A. El-Gammal, and R. A. Bedier, “Synthesis, characterization, optical band gap, in vitro antimicrobial activity and DNA cleavage studies of some metal complexes of pyridyl thiosemicarbazone,” Journal of Molecular Structure, vol. 1035, pp. 307–317, 2013. View at Publisher · View at Google Scholar