DNA Cleavage, Cytotoxic Activities, and Antimicrobial Studies of Ternary Copper(II) Complexes of Isoxazole Schiff Base and Heterocyclic Compounds
Figure 6
Agarose gel electrophoresis patterns for the oxidative cleavage of pBR 322 DNA by 1 and 2(a) and photolytic cleavage of pBR 322 DNA by 1 and 2(b). (a) Lane 1, DNA control; Lane 2, DNA+1 (40 M) + H2O2 (1 mM); Lane 3, DNA+1 (80 M) + H2O2 (1 mM); Lane 4, DNA+1 (120 M) + H2O2 (1 mM); Lane 5, DNA + H2O2 (1 mM) + DMSO (1 mM). Lane 6, DNA+2 (40 M) + H2O2 (1 mM); Lane 7, DNA+2 (80 M) + H2O2 (1 mM); Lane 8, DNA+2 (120 M) + H2O2 (1 mM); (b) Lane 1, DNA control; Lane 2, DNA+1 (40 M) + H2O2 (1 mM); Lane 3, DNA+1 (80 M) + H2O2 (1 mM); Lane 4, DNA+1 (120 M) + H2O2 (1 mM); Lane 5, DNA + DMSO (1 mM). Lane 6, DNA+2 (40 M) + H2O2 (1 mM); Lane 7, DNA+2 (80 M) + H2O2 (1 mM); Lane 8, DNA+2 (120 M) + H2O2 (1 mM).
