Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes against <i>Mycobacterium tuberculosis</i>

<table class="table-group" id="tab8"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Zn(II) complexes</td><td align="center">% Zn content observed (calculated)</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">3a</td><td align="center">9.21 (9.08)</td></tr><tr><td align="left">3b</td><td align="center">8.96 (9.08)</td></tr><tr><td align="left">3c</td><td align="center">8.63 (8.74)</td></tr><tr><td align="left">3d</td><td align="center">6.32 (6.44)</td></tr><tr><td align="left">3e</td><td align="center">7.80 (7.62)</td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">Cu(II) complexes</td><td align="center">% Cu content observed (calculated)</td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">3f</td><td align="center">8.73 (8.85)</td></tr><tr><td align="left">3g</td><td align="center">8.93 (8.85)</td></tr><tr><td align="left">3h</td><td align="center">8.64 (8.52)</td></tr><tr><td align="left">3i</td><td align="center">6.31 (6.27)</td></tr><tr><td align="left">3j</td><td align="center">7.40 (7.42)</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Percentage content of Zn and Cu in metal complexes 3a–3j.

Bioinorganic Chemistry and Applications

tab8

Table 8

Table 8: Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes against <i>Mycobacterium tuberculosis</i> 

Table 8 | Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes against Mycobacterium tuberculosis 