Norfloxacin and N-Donor Mixed-Ligand Copper(II) Complexes: Synthesis, Albumin Interaction, and Anti-Trypanosoma cruzi Activity

Figure 6

X-band EPR spectra for HSA and BSA Cu(II) complexes ((a) and (b), resp.) and for Cu(II)-bipy and Cu(II)-phen complexes with HSA ((c) and (d), resp.). Experimental conditions: Cu, HSA, and BSA 0.5 mM, phosphate buffer 20 mM, and pH 7.4, at 77 K. (b′) and (c′) are the simulated spectra of (b) and (c), using EasySpin [20] with parameters in Table 4.