Research Article

Luminescent Iridium Complex-Peptide Hybrids (IPHs) for Therapeutics of Cancer: Design and Synthesis of IPHs for Detection of Cancer Cells and Induction of Their Necrosis-Type Cell Death

Table 2

Complexation constants of IPHs (assuming 1 : 1 complexation).

AnalyteKapp (M−1)Kd

TRAIL(2.3 ± 0.05) × 1084.3 ± 0.1 nm
5(3.8 ± 0.1) × 1052.7 ± 0.1 μM
6(4.0 ± 0.2)1052.5 ± 0.1 μM
9<104>100 μM
2c<104>100 μM