Synthesis of Amino Acid Schiff Base Nickel (II) Complexes as Potential Anticancer Drugs In Vitro

Scheme 1

Synthetic routes for the preparation of the complexes [Ni (Trp-sal) (phen) (CH₃OH)] (1), [Ni (Trp-(o)-van) (phen) (CH₃OH)]•2CH₃OH (2), and [Ni (Trp-naph) (phen) (CH₃OH)] (3).