Ru(II) Complexes Bearing O, O-Chelated Ligands Induced Apoptosis in A549 Cells through the Mitochondrial Apoptotic Pathway

<div>(a) The intracellular ROS level regulated by <b>Ru-1</b> and <b>Ru-2</b> was detected by an inverted fluorescence microscope. (b) Flow cytometry analysis of intracellular ROS level by DCFH-DA staining after different concentrations of Ru(II) complexes treatment for 12 h.</div>

Bioinorganic Chemistry and Applications

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Figure 5

Figure 5: Ru(II) Complexes Bearing O, O-Chelated Ligands Induced Apoptosis in A549 Cells through the Mitochondrial Apoptotic Pathway 