GE11 Peptide Conjugated Liposomes for EGFR-Targeted and Chemophotothermal Combined Anticancer Therapy

<div>(a), (b) Cytotoxicity and phototoxicity of free CUR/ICG, CUR/ICG-LPs and GE11-CUR/ICG-LPs under the NIR laser irradiation (808 nm) of 1 W·cm<sup>−2</sup> for 5 min at different concentrations on A549 cells after 24 h incubation. (c) Fluorescence images of A549 cells stained with calcein-AM (green) after different treatments. Scale bar = 100 <i>μ</i>m. (d) Synergistic effect of photo- and chemotherapy based on GE11-CUR/ICG-LPs. Cytotoxicity of GE11-ICG-LPs, GE11-CUR-LPs, and GE11-CUR/ICG-LPs with or without laser exposure was performed by MTT assays. 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Bioinorganic Chemistry and Applications

fig5

Figure 5

Figure 5: GE11 Peptide Conjugated Liposomes for EGFR-Targeted and Chemophotothermal Combined Anticancer Therapy 