Synthesis, DNA-Binding, Anticancer Evaluation, and Molecular Docking Studies of Bishomoleptic and Trisheteroleptic Ru-Diimine Complexes Bearing 2-(2-Pyridyl)-quinoxaline

Table 6

Binding constants and Stern–Volmer quenching constants of Ru (II) complexes at 25°C.

Compound	Kb (M^−1)	KSV (M^−1)	Kq (M^−1s^−1)	Kapp (M^−1)	Βinding mode	References
1		0.87	3.4·10^11	6·10^4
2	4.46·10^5	0.96	1.8·10^12	9·10^4
[Ru(phen)2(cd2, 2’-pq)]^+2	4.67 10^3	0.052		4.67·10^3	Groove binding	[56]
[RuCl3(dmso) (phen)]		3.03		6.9·10^6	Intercalation	[57]
[RuCl3(dmso) (bpy)]		1.73		3.43·10^6		[57]
[RuCl3(dmso) (dppz)]		4.47		8.62·10^6	Intercalation	[57]
[Ru(aeip)2(Haip)]^2+	4.47·10^6	3.26			Groove binding	[58]