Research Article
Synthesis, Structure, and Biologic Activity of Some Copper, Nickel, Cobalt, and Zinc Complexes with 2-Formylpyridine N4-Allylthiosemicarbazone
Table 5
The percentage of viability (V) of Daphnia magna in the presence of different concentrations of studied compounds and the corresponding LC50 values.
| | Compound | V, (%) | LC50, μM | | 100 μM | 10 μM | 1 μM | 0.1 μM |
| | HL | 0.0 | 0.0 | 56.4 ± 7.3 | 97 ± 7.3 | 1.0 ± 0.1 | | [Zn(H2O) (L)Cl] (1) | 0.0 | 0.0 | 56.4 ± 7.3 | 102.6 ± 0.0 | 1.0 ± 0.1 | | [Cu(L)Cl] (2) | 0.0 | 0.0 | 97.4 ± 7.3 | 102.6 ± 0.0 | 3.5 ± 2.8 | | [Cu(L)Br] (3) | 0.0 | 0.0 | 97.4 ± 7.3 | 102.6 ± 0.0 | 3.5 ± 2.8 | | [Cu2L2(CH3COO)2]·4H2O (4) | 0.0 | 0.0 | 66.7 ± 7.3 | 76.9 ± 7.3 | 1.3 ± 0.5 | | [Ni(HL)2]Cl2·H2O (5) | 87.2 ± 7.3 | 97.4 ± 7.3 | 102.6 ± 0.0 | 102.6 ± 0.0 | >100 | | [Co(L)2]Cl (6) | 35.9 ± 7.3 | 92.3 ± 0.0 | 97.4 ± 7.3 | 97.4 ± 7.3 | 65.4 ± 11.8 | | Doxorubicin | 0.0 | 25.6 ± 7.3 | 76.9 ± 7.3 | 87.2 ± 7.3 | 3.3 ± 1.1 |
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