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Nanoparticles and Metal-Based Compounds as Imaging and Therapeutic Agents

Call for Papers

Recent research has shown important progress in the use of nanoparticles and metal-based compounds as the diagnostic and therapeutic agents. In the past, paclitaxel, 5-fluorouracil, and platinum-based drugs, especially cisplatin and carboplatin, have dominated the treatment of various types of cancers due to their pharmacological properties. However, the clinical utilization of mentioned drugs has often been limited by their severe side effects which increased the interest for the development of alternative therapeutic strategies. A large number of newly synthesized metal-based compounds expressed high antimicrobial and antitumor activity, both in vitro and in vivo. Because of their extremely small size and high surface area, nanoparticles offer a number of advantages over traditional materials and are suitable for a wide variety of biomedical applications, particulalry in drug delivery and imaging. Recently, great attention of scientific community has been attracted to the nanoparticles containing metal based compounds as potentially new agents in diagnosis and therapy of human diseases.

Accordingly, the focus of this special issue will be to shed further light on the use of nanoparticles and metal based compounds as new imaging and therapeutic agents. We would like to invite you to submit original research papers and reviews to this issue.

Potential topics include but are not limited to the following:

  • Synthesis and spectral characterizaton of new metal-based compounds
  • Determination of kinetics and mechanism of interaction between biomolecules (including DNA and proteins) and novel metal-based compounds
  • Molecular mechanisms involved in antimicrobial and antitumor activity of metal-based compounds
  • Therapeutic potential of new metal-based compounds tested in animal models of tumors
  • Preparation and characterization of nanoparticles for drug delivery and imaging
  • In vitro and in vivo study of nanoparticles containing metal based compounds
  • Potential detrimental effects of nanoparticles

Authors can submit their manuscripts through the Manuscript Tracking System at

Submission DeadlineFriday, 10 November 2017
Publication DateMarch 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

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