Innovative Analyses Support a Role for DNA Damage and an Aberrant Cell Cycle in Myelodysplastic Syndrome Pathogenesis

Table 3

p-H2A.X and Annexin V reactivity in marrow cells.

	p-H2A.X (%)		Annexin V (%)
	Controls; (𝑛=20)	MDS; (𝑛=17)	Controls; (𝑛=20)	MDS; (𝑛=17)
nRBC	1.5; (0.4–3.7)	8.0; (0.1–49.9)	19.4; (3.1–54.6)	12.3; (2.2–55.3)
Myeloid	1.1; (0.1–4.6)	15.9; (0.2–51.0)	16.4; (4.0–58.0)	24.2; (1.2–89.7)
CD34+	1.7; (0.2–4.9)	1.7; (0.0–5.1)	11.6; (3.8–26.5)	11.9; (1.9–61.5)

Cell populations discriminated by CD45, SS, CD71, and CD34.
Results expressed as mean (%) positive (range).