Differential Expression of Matrix Metalloproteinase-2 Expression in Disseminated Tumor Cells and Micrometastasis in Bone Marrow of Patients with Nonmetastatic and Metastatic Prostate Cancer: Theoretical Considerations and Clinical Implications—An Immunocytochemical Study

Figure 3

(a) Micrometastasis PSA (+). (b) Biopsy PSA (−). (c) Borders of microfragment MMP-2 (+). (d) Central pattern MMP-2 (+) stromal cells MMP-2 (+). (e) Central pattern MMP-2. (f) Microfragment MMP-2 (−), surrounding stromal cells MMP-2 (−). (g) Borders of microfragment MMP-2 (+), surrounding stromal cells MMP-2 (−). (h) Microfragment MMP-2 (−), stromal cells MMP-2 (−), DTC MMP-2 (+). (i) Borders of microfragment MMP-2 (+), some stromal cells MMP-2 (+).

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