Table 2: Demographic variables according to Gleason score.

Gleason 4Gleason 5 + 6Gleason 7Gleason 8 + 9 = (statistical test)

No. of patients ( )281063120
Mean age ± SD (years)71.1 ± 8.773.2 ± 9.470 ± 8.971.7 ± 6.7NS 
(ANOVA)
Median serum PSA (IQR) ng/mL1.0 (0.5–4.8)1.68 (0.5–5.5)0.57 (0.1–10.0)1.68 (0.32–28.7)NS 
(Kruksal-Wallis)
Median stage (IQR)2 (1-2)a,b,c3 (2-3)a,d3 (2-3)b3 (3-4)c,da-a < 0.001 
b-b < 0.001 
c-c < 0.001 
d-d < 0.002 
Kruksal-Wallis
(significant <0.004)
Median time from diagnosis (IQR) (years)2 (1–4)4 (1–8)3 (1–5)2 (1–5)NS (Kruksal-Wallis)
Detection prostate cells % ( )Chi-squared
Log regression
 CPC46.4% (13)63.2 (67)64.5 (20)80 (16)
 DTC35.7% (10)65.1(69)67.7 (21)75 (15)
 mM32.1% (9)77.4 (82)77.4 (24)85 (17)

IQR: interquartile range, CPC: circulating prostate cell, DTC: disseminated tumor cell, mM: micrometastasis, and NS: not significant.