Inhibition of Mammalian Target of Rapamycin in Human Acute Myeloid Leukemia Cells Has Diverse Effects That Depend on the Environmental In Vitro Stress
Figure 4
The effect of the HDAC inhibitor valproic acid on the expression ATG-3 (a), ATG-10 (b) and bcl-XL (c) when primary human on AML cells from unselected patients were cultured in serum-free medium in the presence of rapamycin 100 nM alone or in combination with valproic acid (2400 μM). The results are presented as the MFI, and the values are given below each figure. Abbreviations: Vla, valproic acid; Rapa, rapamycin.
