Review Article
Unrelated Hematopoietic Stem Cell Donor Matching Probability and Search Algorithm
Table 1
Parameters that contribute to define a low probability estimate.
| HLA, ethnicity, nb donors | Examples and comments |
| ≤3 donors in BMDW | | Non-European ancestry | | Rare(1) allele at any locus | A*02:17, B*44:05, DRB1*11:03 | Rare B-C association | B*18:01-C*02:02, B*51:01-C*16:02 | Rare DRB1-DQB1 association | DRB1*15:01-DQB1*06:03, DRB1*0701-DQB1*03:02 | B*15:01, B*18:01, B*27:05, B*51:01-positive haplotypes | Higher risk of C MM | B*35:02/35:03/35:08-positive haplotypes | Higher risk of B*35 allele MM |
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(1)<5% of the alleles included a given serotype.
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