Bone Marrow Research / 2012 / Article / Tab 1

Review Article

What Is the Most Appropriate Source for Hematopoietic Stem Cell Transplantation? Peripheral Stem Cell/Bone Marrow/Cord Blood

Table 1

Comparison of the stem cell sources.

Cord BloodPBBM

Risk for the donorNoneYesYes

Duration of searching (month)≤13–63–6

Factors limiting the engraftmentCell countHLA matchHLA match

Dominant factor affecting the outcomeEngraftment failure
delayed immune recovery

Minimal HLA match4/69/109/10

Risk for GVHD LowHighHigh

DLI possibilityNonePossiblePossible

Posttransplant infection riskHigherHighHigh

Immunotheraphy possibilityNoneYesYes

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