What Is the Most Appropriate Source for Hematopoietic Stem Cell Transplantation? Peripheral Stem Cell/Bone Marrow/Cord Blood

Table 1

Comparison of the stem cell sources.

	Cord Blood	PB	BM
Risk for the donor	None	Yes	Yes
Duration of searching (month)	≤1	3–6	3–6
Factors limiting the engraftment	Cell count	HLA match	HLA match
Dominant factor affecting the outcome	Engraftment failure; delayed immune recovery	GVHD	GVHD
Minimal HLA match	4/6	9/10	9/10
Risk for GVHD	Low	High	High
Acute	Low	High	High
Chronic	Low	Higher	High
DLI possibility	None	Possible	Possible
Posttransplant infection risk	Higher	High	High
Immunotheraphy possibility	None	Yes	Yes