Research Article

Combination of Complement-Dependent Cytotoxicity and Relative Fluorescent Quantification of HLA Length Polymorphisms Facilitates the Detection of a Loss of Heterozygosity

Table 3

HLA class I and class II typing before and after HSCT (Case A).

HLA class IA*-1A*-2B*-1B*-2C*-1C*-2

Patient before Tx03 : 0124 : 0207 : 0213 : 0206 : 0207 : 02
Sister03 : 0124 : 0207 : 0208 : 0107 : 0107 : 02
Patient (pB) after Tx03 : 01 24 : 02 07 : 02 08 : 01 07 : 01 07 : 02
LAIP pos. cells03 : 0107 : 0207 : 02

HLA class IIDRB1*-1DRB1*-2DQB1*-1DQB1*-2DPB1*-1DPB1*-2

Patient before Tx01 : 0107 : 0102 : 0205 : 01n.d.n.d.
Sister01 : 0103 : 0102 : 0105 : 01n.d.n.d.
Patient (pB) after Tx01 : 01 03 : 01 02 : 01 05 : 01 04 : 01 04 : 01
LAIP pos. cells01 : 0105 : 0104 : 01

Abbreviations: pB: peripheral blood; LAIP: leukemia-associated aberrant immunophenotypes; n.d.: no data.