Antimicrobial-Induced Cytopenia and Bone Marrow Hypocellularity in Patients with Cirrhosis

Table 3

Cytopenias among those who received antimicrobials and those who did not (Total ).

Antimicrobial agent	Parameter	Those who received	Those who did not receive	OR (95% CI)	value
Cephalosporins; ()	Anemia	53.5%	38.2%	1.91 (0.073–3.409)	0.128
	Leucopenia	36%	33.6%	1.08 (0.597–1.957)	0.796
	Thrombocytopenia	58.1%	58.2%	1.00 (0.565–1.775)	0.995
Carbapenems; ()	Anemia	50%	43.6%	1.294 (0.645–2.595)	0.468
	Leucopenia	27.5%	36.5%	0.659 (0.306–1.418)	0.286
	Thrombocytopenia	57.5%	58.3%	0.966 (0.478–1.952)	0.924
Beta-lactams; ()	Anemia	56%	43.3%	1.667 (0.716–3.886)	0.236
	Leucopenia	40%	33.9%	1.299 (0.549–3.071)	0.551
	Thrombocytopenia	68%	36.7%	1.621 (1.464–2.960)	0.041
Quinolones; ()	Anemia	53.8%	44.3%	1.469 (0.475–4.542)	0.504
	Leucopenia	30.8%	35%	0.826 (0.245–2.789)	0.759
	Thrombocytopenia	76.9%	46.8%	1.532 (1.474–2.507)	0.039
Antifungals; ()	Anemia	57.9%	43.5%	1.786 (0.685–4.654)	0.236
	Leucopenia	31.6%	35%	0.856 (0.310–2.363)	0.764
	Thrombocytopenia	57.9%	58.2%	0.988 (0.379–2.576)	0.980