BioMed Research International

BioMed Research International / 2002 / Article
Special Issue

DNA Damage, Repair, and Diseases

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Review article | Open Access

Volume 2 |Article ID 465248 |

Anna A. Friedl, "Ku and the Stability of the Genome", BioMed Research International, vol. 2, Article ID 465248, 5 pages, 2002.

Ku and the Stability of the Genome

Received01 Nov 2001
Revised26 Nov 2001
Accepted11 Dec 2001


Ku proteins are associated with a variety of cellular processes such as repair of DNA-double-strand breaks, telomere maintenance and retrotransposition. In recent years, we have learned a lot about their cellular and molecular functions and it has turned out that Ku-dependent processes affect the stability of the genome, both positively and negatively, in several ways. This article gives an overview on the role of Ku in determining the shape of the genome.

Copyright © 2002 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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