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Journal of Biomedicine and Biotechnology
Volume 2, Issue 3, Pages 117-119
Mini-Review Article

Vectorial Transcellular Calcium Transport in Intestine: Integration of Current Models

1Department of Nutrition and Food Sciences and the Biotechnology Center, Utah State University, Logan, UT 85322-8700, USA
2Fish Endocrinology Laboratory, Department of Zoology/Zoophysiology, Göteborg University, Box 463, Göteborg SE-405 30, Sweden

Received 19 March 2002; Accepted 29 April 2002

Copyright © 2002 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In spite of decades of research, the exact subcellular pathway for calcium transport in intestine has not been elucidated. In this mini-review, we present three models for vectorial movement of calcium across the cell: facilitated (cytoplasmic) diffusion, vesicular/lysosomal transport, and tunneling through the endoplasmic reticulum compartment. We conclude by offering one way to integrate elements of these three models.