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Journal of Biomedicine and Biotechnology
Volume 2006 (2006), Article ID 82323, 6 pages
Oxidative Damage to RNA in Neurodegenerative Diseases
1Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa 078-8510, Japan
2Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan
3Department of Neurology, School of Medicine, Tohoku University, Sendai 980-8574, Japan
4Pharmaceutical Research Laboratories I, Pharmaceutical Research Division, Takeda Chemical Industries Limited, Osaka 532-8686, Japan
5Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA
Received 5 January 2006; Accepted 21 April 2006
Copyright © 2006 Akihiko Nunomura et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [64 citations]
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- Lucia Petrozzi, Giulia Ricci, Noemi J. Giglioli, Gabriele Siciliano, and Michelangelo Mancuso, “Mitochondria and neurodegeneration,” Bioscience Reports, vol. 27, no. 1-3, pp. 87–104, 2007.
- Mark A. Lovell, and William R. Markesbery, “Oxidative damage in mild cognitive impairment and early Alzheimer's disease,” Journal of Neuroscience Research, vol. 85, no. 14, pp. 3036–3040, 2007.
- Boris Görg, Natalia Qvartskhava, Verena Keitel, Hans J. Bidmon, Oliver Selbach, Freimut Schliess, and Dieter Häussinger, “ Ammonia induces RNA oxidation in cultured astrocytes and brain in vivo ,” Hepatology, vol. 48, no. 2, pp. 567–579, 2008.
- Joshua A. Sonnen, John C. Breitner, Mark A. Lovell, William R. Markesbery, Joseph F. Quinn, and Thomas J. Montine, “Free radical-mediated damage to brain in Alzheimer's disease and its transgenic mouse models,” Free Radical Biology and Medicine, vol. 45, no. 3, pp. 219–230, 2008.
- Dieter Häussinger, and Schliess, “Pathogenetic mechanisms of hepatic encephalopathy,” Gut, vol. 57, no. 8, pp. 1156–1165, 2008.
- Mark A. Lovell, and William R. Markesbery, “Oxidatively modified RNA in mild cognitive impairment,” Neurobiology of Disease, vol. 29, no. 2, pp. 169–175, 2008.
- Carmela Fimognari, Piero Sestili, Monia Lenzi, Anahi Bucchini, Giorgio Cantelli-Forti, and Patrizia Hrelia, “RNA as a new target for toxic and protective agents,” Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 648, no. 1-2, pp. 15–22, 2008.
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- M W Miller, and N Sadeh, “Traumatic stress, oxidative stress and post-traumatic stress disorder: neurodegeneration and the accelerated-aging hypothesis,” Molecular Psychiatry, 2014.
- Jamie L. Lim, Micha M. M. Wilhelmus, Helga E. de Vries, Benjamin Drukarch, Jeroen J. M. Hoozemans, and Jack van Horssen, “Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases,” Archives of Toxicology, 2014.
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- Carmela Protano, Roberta Andreoli, Antonio Mutti, Stefano Petti, and Matteo Vitali, “Biomarkers of oxidative stress to nucleic acids: Background levels and effects of body mass index and life-style factors in an urban paediatric population,” Science of The Total Environment, vol. 500-501, pp. 44–51, 2014.
- Sasan Andalib, Manouchehr Seyedi Vafaee, and Albert Gjedde, “Parkinson's disease and mitochondrial gene variations: A review,” Journal Of The Neurological Sciences, vol. 346, no. 1-2, pp. 11–19, 2014.
- Taichi Kashiwagi, Hanxu Yan, Takeki Hamasaki, Tomoya Kinjo, Noboru Nakamichi, Kiichiro Teruya, Shigeru Kabayama, and Sanetaka Shirahata, “Electrochemically Reduced Water Protects Neural Cells from Oxidative Damage,” Oxidative Medicine and Cellular Longevity, vol. 2014, pp. 1–18, 2014.
- Rebecca K. Lane, Tyler Hilsabeck, and Shane L. Rea, “The Role of Mitochondrial Dysfunction in Age-Related Diseases,” Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2015.
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