Case Report

De Novo Balanced Translocation t (7;16) (p22.1; p11.2) Associated with Autistic Disorder

Figure 3

FISH analysis of the translocation breakpoints: (a) FISH analysis with the BAC RP11-730B22 (green) located in 7p22.1 and a centromeric probe of chromosome 16 (red), shows that this BAC is spanning the breakpoint on chromosome 7. (b) FISH analysis with BACs RP11-264M14 (green) showed that it spans the translocation breakpoint located on 16p11.2. It was hybridised with a chromosome 7 centromeric probe (red). (Chr.: chromosome, Der.: derivative).
231904.fig.003a
(a)
231904.fig.003b
(b)