Peptide Mimicrying Between SARS Coronavirus Spike Protein and Human Proteins Reacts with SARS Patient Serum
Figure 2
Sequence homology between S protein, (a) human Angrgm-52, and (b) bradykinin. Spike protein
sequence (protein databank NP_828851) was compared with sequences from all nonredundant GenBank CDS translations, PDB,
SwissProt, PIR, and PRF of human, by using blastp (NCBI, NIH, USA). For Panel
(a), BLASTP was used to calculate the similarity between S protein and human
Angrgm-52, with matrix set at default. For an identical residue, one letter symbol of amino is shown between
the two sequences, and for a conservative substation, “+” is shown. For Panel (b), pairwise alignment was
calculated based on Smith-Water local alignment with matrix set at BLOSUM 45. “” is annotated for
identical residues; “:” and “.” are for similar residues.
