Jaceosidin Induces Apoptosis in Human Ovary Cancer Cells through Mitochondrial Pathway
Figure 1
(a) Structure of jaceosidin. (b) Jaceosidin inhibits
proliferation of CAOV-3, SKOV-3, PC3, and HeLa cells in a concentration-dependent
manner. Cells were cultured in 96-well-plate for first 24 hours. Then, they
were treated with different concentrations of jaceosidin for further 48 hours. (c)
Jaceosidin inhibits proliferation in CAOV-3 cells in a time-dependent manner.
The CAOV-3 cells were incubated with jaceosidin for 24, 48, and 72 hours,
respectively. MTT assay was used to evaluate the proliferation rate. Each datum
indicated mean ± s.d. of three independent experiments. , versus control (Dunnett’s test).