Protein Alterations in Infiltrating Ductal Carcinomas of the Breast as Detected by Nonequilibrium pH Gradient Electrophoresis and Mass Spectrometry
Figure 3
Overexpression of α-B crystallin in infiltrating ductal carcinoma tissues of
the breast. Formalin-fixed, paraffin-embedded sections were immunostained with
rabbit polyclonal antibody against α-B crystallin. Tissues were stained with
hematoxylin and viewed by light microscopy. A strong staining (brown) in tumor
cells (T) has been observed, whereas α-B crystallin was expressed at lower
levels in normal epithelial cells. (a) α-B crystallin expression in IDCA
tissues (200x magnification), (b)-(c) α-B crystallin expression in IDCA (400x
magnification), (d) α-B crystallin expression in nontumor tissues (400x
magnification).
