Duchenne and Becker Muscular Dystrophy: Contribution of a Molecular and Immunohistochemical Analysis in Diagnosis in Morocco

Table 1

Clinical data, and genetic and immunohistochemical results for our patients.

N^∘	Age (years)	Age at onset (years)	Consanguinity	Immunochemistry			Deleted exons	Other criterion
				Dys-C	α-SG	γ-SG
1	13	5	No	−	+++	+++	50, 51, and 52	Elevated SCK activity at the mother
2	9	3	No	−	+++	+++	45, 47, 48, 50, 51, and 52	Maternal uncle died
3	12	4	No	−	+++	+++	51 and 52	Elevated SCK activity at the mother
4	16	5	No	−	+++	+++	−	Elder brother with the same symptoms
5	11	3	Yes	−	+++	+++	45 and 48	−
6	13	3	No	−	+++	+++	45	−
7	12	5	No	+/−	+++	+++	12, 13, 17, 19, 43, 44, 45, 47, and 48	—
8	13	5	Yes	+/−	+++	+++	3, 4, 6, and 8	−
9	13	2	Yes	+	+	+	48	521del T in γ-SG gene not found
10	19	11	Yes	+++	+	+	Pm	521del T in γ-SG gene not found

+++: normal; +: reduced; +/−: irregular; − : absent
N^∘: patient number; SG: sarcoglycan; Dys: dystrophin; SCK: serum creatine kinase.