Research Article

Clinical Significance of Epigenetic Inactivation of hMLH1 and BRCA1 in Tunisian Patients with Invasive Breast Carcinoma

Figure 2

Representative result of p53 immunohistochemical staining and hMLH1 promoter methylation. (a) Breast tumor specimen with p53 nuclear positivity associated with both hMLH1 methylated and unmethylated DNA. (b) Breast tumor specimen negative for p53 correlated with unmethylated hMLH1 profile.
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(a)
369129.fig.002b
(b)